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. 2021 Jun 8;13(12):2871. doi: 10.3390/cancers13122871

Table 1.

Histological subtypes of Primary liver cancers (PLCs) and prognosis.

Prognosis
Hepatocellular Carcinoma (HCC) Better Worse
Histological subtypes Lymphocyte-rich Clear cell Macrotrabecular-massive Neutrophil-rich
Tumor differentiation well poor
Immunohistochemical subtype K19 negative HCC K19-positive HCC
Immuno microenvironment Immune-high Immune-low
Combined HCC-CCA
Tumor component Predominant HCC component Predominant iCCA component
Intrahepatic cholangiocarcinoma (iCCA)
Histological subtypes Small duct type Large duct type

As compared with the prognosis of each category.