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. 2021 Jun 22;11(6):e047341. doi: 10.1136/bmjopen-2020-047341

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Proportion of clinical trials started monthly that use connected digital products for telehealth delivery or remote monitoring. The preperiod and postperiod analysis windows include the 10 months before and after the COVID-19 pandemic onset. Percentages on the left and right represent the average percentage of trials using connected digital products during the preperiod and postperiod, respectively. *Statistical significance in the mean difference between the preperiods and postperiods using two-sided proportion tests. Source: authors’ analysis of ClinicalTrials.gov data.