Table 4.

List of genes mediating stronger HOCl-resistance.

Gene	Known or Projected Functions
prpE	Propionate-CoA ligase; catalyzes the synthesis of propionyl-CoA from propionate and CoA [31].
frmB	S-formylglutathione hydrolase; hydrolyzes S-formylglutathione to glutathione and formate [45].
rutC	Putative aminoacrylate peracid reductase [46].
sucC	Succinate-CoA ligase (ADP-forming) subunit beta; functions in the citric acid cycle [47].
ycbB	Periplasmic L,D-transpeptidase; plays a role in the protective remodeling of peptidoglycan during cell envelope stress [48].
yccJ	PF13993 family protein.
hyaC	Probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit; functions in anchoring hydrogenase to the membrane [49].
hyaE	Hydrogenase-1 operon protein [50].
tap	Methyl-accepting chemotaxis protein IV [51].
yoaE	UPF0053 inner membrane protein; putative transport protein [52].
motB	Motility protein B; comprises the stator element of the flagellar motor complex with MotA [53].
rnc	Ribonuclease 3 for rRNA processing [54].
elaA	Putative N-acetyltransferase.
yfdY	DUF2545 domain-containing protein [55].
exbD	A component of the energy-transducing Ton system [56].
ilvA	Threonine deaminase; carries out the first step in the synthesis of isoleucine [41].
yhdJ	Overexpression of YdhJ leads to methylation of genomic DNA at the NsiI recognition sequence (5′-ATGCAT-3′) [57].
ytfI	Uncharacterized gene.
ybhR	One of two integral membrane subunits of a putative ABC exporter [58].
yedQ	A probable inner membrane protein whose expression is dependent on σS under a number of stress conditions [59].
marC	An inner membrane protein with six predicted transmembrane domains [52].
sanA	Multi-copy expression of sanA complements the vancomycin sensitivity of an E. coli K-12 mutant with outer membrane permeability defects [60].
rsuA	Pseudo-uridine synthase that is responsible for pseudouridylation of 16S rRNA at position 516 [61].