Table 2.
HER2-Positive (n = 19) |
HER2-Negative (n = 123) |
||||
---|---|---|---|---|---|
Features | Cases | Percentage% | Cases | Percentage% | p |
Age | 0.085 | ||||
Mean | 61 | 66 | |||
≤70 | 14 | 16.86% | 70 | 84.33% | |
≥71 | 5 | 8.47% | 53 | 91.53% | |
Sex | 0.578 | ||||
Male | 13 | 14.60% | 76 | 85.40% | |
Female | 6 | 11.30% | 47 | 88.70% | |
Location | 0.041 | ||||
Cardia | 1 | 4.30% | 22 | 95.70% | |
Fundus | 1 | 100% | 0 | 0.0% | |
Corpus | 8 | 13.80% | 50 | 86.20% | |
Antrum | 9 | 15.30% | 50 | 84.70% | |
Histological type | 0.013 | ||||
Intestinal | 16 | 21.10% | 60 | 78.90% | |
Diffuse | 2 | 3.50% | 55 | 96.50% | |
Mixed | 1 | 11.10% | 9 | 88.90% | |
Pathological diagnosis | 0.267 | ||||
Adenocarcinoma | 18 | 17.30% | 86 | 82.70% | |
Signet ring cell carcinoma | 1 | 2.90% | 33 | 97.10% | |
Small cell carcinoma | 0 | 0.00% | 2 | 100% | |
Undifferentiated carcinoma | 0 | 0.00% | 1 | 100% | |
Squamous cell carcinoma | 0 | 0.00% | 1 | 100% | |
Degree of differentiation | 0.178 | ||||
G1 | 0 | 0.00% | 18 | 100% | |
G2 | 8 | 17.40% | 38 | 82.60% | |
G3 | 11 | 14.90% | 63 | 85.10% | |
T | 0.25 | ||||
Tis | 0 | 0.00% | 6 | 100% | |
T1a/T1b | 0 | 0.00% | 15 | 100% | |
T2 | 1 | 4.80% | 20 | 95.20% | |
T3 | 11 | 19.30% | 46 | 80.70% | |
T4a/T4b | 7 | 16.27% | 36 | 83.73% | |
N | 0.455 | ||||
N0 | 5 | 9.30% | 49 | 90.70% | |
N1 | 5 | 13.20% | 33 | 86.80% | |
N2 | 3 | 13.00% | 20 | 87.00% | |
N3a/N3b | 6 | 22.20% | 21 | 77.80% | |
M | 0.005 | ||||
M0 | 14 | 10.90% | 115 | 89.10% | |
M1 | 5 | 38.50% | 8 | 61.50% | |
Stage | 0.012 | ||||
IA/IB | 1 | 3.10% | 32 | 96.90% | |
IIA/IIB | 6 | 12.80% | 41 | 87.20% | |
IIIA/IIIB/IIIC | 6 | 13.00% | 40 | 87.00% | |
IV | 6 | 37.50% | 10 | 62.50% | |
Lymphatic involvement | 0.227 | ||||
Yes | 11 | 17.20% | 53 | 82.80% | |
No | 8 | 10.30% | 70 | 89.70% | |
Vascular involvement | 0.292 | ||||
Yes | 10 | 16.90% | 49 | 83.10% | |
No | 9 | 10.80% | 74 | 89.20% | |
Perineural involvement | 0.763 | ||||
Yes | 7 | 14.60% | 41 | 85.40% | |
No | 12 | 12.80% | 82 | 87.20% | |
Adjuvant chemotherapy | 0.005 | ||||
Yes | 11 | 25.60% | 32 | 74.40% | |
No | 8 | 8.10% | 91 | 91.90% | |
Survival | 0.209 | ||||
Living | 5 | 8.90% | 51 | 91.10% | |
Deceased | 14 | 16.30% | 72 | 83.70% |
HER2: Human Epidermal Growth Receptor 2.