Skip to main content
. 2021 May 25;11(6):944. doi: 10.3390/diagnostics11060944

Table 2.

Clinical and pathological features of the 142 gastric cancer patients and correlation with HER2 status.

HER2-Positive
(n = 19)
HER2-Negative
(n = 123)
Features Cases Percentage% Cases Percentage% p
Age 0.085
Mean 61 66
≤70 14 16.86% 70 84.33%
≥71 5 8.47% 53 91.53%
Sex 0.578
Male 13 14.60% 76 85.40%
Female 6 11.30% 47 88.70%
Location 0.041
Cardia 1 4.30% 22 95.70%
Fundus 1 100% 0 0.0%
Corpus 8 13.80% 50 86.20%
Antrum 9 15.30% 50 84.70%
Histological type 0.013
Intestinal 16 21.10% 60 78.90%
Diffuse 2 3.50% 55 96.50%
Mixed 1 11.10% 9 88.90%
Pathological diagnosis 0.267
Adenocarcinoma 18 17.30% 86 82.70%
Signet ring cell carcinoma 1 2.90% 33 97.10%
Small cell carcinoma 0 0.00% 2 100%
Undifferentiated carcinoma 0 0.00% 1 100%
Squamous cell carcinoma 0 0.00% 1 100%
Degree of differentiation 0.178
G1 0 0.00% 18 100%
G2 8 17.40% 38 82.60%
G3 11 14.90% 63 85.10%
T 0.25
Tis 0 0.00% 6 100%
T1a/T1b 0 0.00% 15 100%
T2 1 4.80% 20 95.20%
T3 11 19.30% 46 80.70%
T4a/T4b 7 16.27% 36 83.73%
N 0.455
N0 5 9.30% 49 90.70%
N1 5 13.20% 33 86.80%
N2 3 13.00% 20 87.00%
N3a/N3b 6 22.20% 21 77.80%
M 0.005
M0 14 10.90% 115 89.10%
M1 5 38.50% 8 61.50%
Stage 0.012
IA/IB 1 3.10% 32 96.90%
IIA/IIB 6 12.80% 41 87.20%
IIIA/IIIB/IIIC 6 13.00% 40 87.00%
IV 6 37.50% 10 62.50%
Lymphatic involvement 0.227
Yes 11 17.20% 53 82.80%
No 8 10.30% 70 89.70%
Vascular involvement 0.292
Yes 10 16.90% 49 83.10%
No 9 10.80% 74 89.20%
Perineural involvement 0.763
Yes 7 14.60% 41 85.40%
No 12 12.80% 82 87.20%
Adjuvant chemotherapy 0.005
Yes 11 25.60% 32 74.40%
No 8 8.10% 91 91.90%
Survival 0.209
Living 5 8.90% 51 91.10%
Deceased 14 16.30% 72 83.70%

HER2: Human Epidermal Growth Receptor 2.