Table 3.
The relationship between reproductive factors and breast cancer risk using TMLE and super learner approach (787 Cases, 928 Controls) in Fars province, Iran, 2009
| Reproductive factors | Risk Differencesa (95% CI) |
Risk ratio (95% CI) |
PAF (%) (95% CI) |
|---|---|---|---|
| Parity (> 3) | 6.6 (−14.6, 36.7) | 1.1 (0.8, 1.5) | 3.6 (−8.5, 20.2) |
| Menopausal status (yes) | 69.4 (68.0, 70.0) | 3.3 (2.3, 4.6) | 40.3 (39.5, 40.6) |
| Age at first pregnancy (≥25 years) | 2.2 (−33.6, 38.1) | 1.1 (0.6, 1.7) | 1.16 (1.16, 1.17) |
| Age at first marriage (≥20 years) | 37.0 (6.4, 60.1) | 1.6 (1.3, 2.1) | 14.5 (2.5, 23.5) |
| Breastfeeding duration (≤60) | 45.3 (38.4, 51.1) | 1.8 (1.3, 2.5) | 27.3 (23.1, 30.8) |
| OC use (yes) | 37.9 (16.8, 56.2) | 1.6 (1.3, 2.1) | 24.4 (10.5, 35.5) |
CI confidence interval, OC oral contraceptive, PAF population attributable fraction. a per 100,000