Table 2.
The total weight gain, organ weight and blood biochemical index of rats in each group.
| Parameters | Groups | ||||
|---|---|---|---|---|---|
| Control | HC | HC-Lovastatin | HC-E. faecium Strain 132 | HC-L. paracasei Strain 201 | |
| Weigh gained (g/6 weeks) | 155.02 ± 32.60 | 184.31 ± 26.32 ### | 147.03 ± 30.68 *** | 156.91 ± 20.57 ** | 165.14 ± 22.65 ** |
| Cardiac index | 0.29 ± 0.03 | 0.30 ± 0.03 | 0.29 ± 0.04 | 0.31 ± 0.03 | 0.30 ± 0.02 |
| Liver index | 2.50 ± 0.35 | 3.79 ± 0.60 ### | 3.11 ± 0.25 ** | 3.10 ± 0.51 * | 2.95 ± 0.46 ** |
| Spleen index | 0.19 ± 0.02 | 0.21 ± 0.09 | 0.18 ± 0.04 | 0.19 ± 0.04 | 0.22 ± 0.09 |
| Kidney index | 0.60 ± 0.06 | 0.57 ± 0.07 | 0.54 ± 0.08 | 0.56 ± 0.05 | 0.55 ± 0.08 |
| Epididymal fat index | 0.99 ± 0.18 | 1.41 ± 0.29 ## | 0.98 ± 0.19 * | 1.08 ± 0.12 * | 0.99 ± 0.14 * |
| TBA(μmol/L) | 13.98 ± 5.81 | 14.52 ± 5.99 | 13.51 ± 7.78 | 13.97 ± 3.92 | 14.47 ± 8.15 |
| TG (mmol/L) | 0.33 ± 0.11 | 0.63 ± 0.12 ### | 0.24 ± 0.09 **** | 0.38 ± 0.08 ** | 0.40 ± 0.04 ** |
| LDL-C(mmol/L) | 0.27 ± 0.04 | 0.93 ± 0.06 #### | 0.67 ± 0.22 ** | 0.71 ± 0.11 * | 0.69 ± 0.05 * |
| HDL-C(mmol/L) | 0.46 ± 0.19 | 0.26 ± 0.04 ## | 0.25 ± 0.07 | 0.29 ± 0.05 | 0.28 ± 0.05 |
| TC (mmol/L) | 1.42 ± 0.23 | 1.91 ± 0.70 # | 1.63 ± 0.53 | 1.71 ± 0.15 | 1.69 ± 0.31 |
Organs index = (organ weight/total weight) ×100; p-values were determined using a one-way ANOVA with Tukey’s test for post-hoc analysis, n = 6. Significant differences between the HC group versus control group are indicated as # p < 0.05, ## p < 0.01, ### p < 0.01, #### p < 0.0001. Significant differences between the HC-lovastatin, HC-E. faecium strain 132 or HC-L. paracasei strain 201 group versus from HC group are indicated as * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. TBA, total bile acid; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol.