Table 1.

Statistical evaluation of relative NF-ĸB and PXR activities after different exposure times of LS180 cells to two different IFN-α 2a concentrations.

Exposure Time	NF-ĸB Activity		PXR Activity
	IFN-α 2a 1000 U/mL	IFN-α 2a 5000 U/mL	IFN-α 2a 1000 U/mL	IFN-α 2a 5000 U/mL
2 h	<0.0001	<0.0001	0.546	0.666
6 h	0.0078	0.002	<0.0001	<0.0001
24 h	<0.0001	<0.0001	<0.0001	<0.0001
30 h	0.010	0.0003	<0.0001	<0.0001

Shown are p values evaluated by a nonparametric, unpaired, two-sided Mann–Whitney U-test. Significant changes (p ≤ 0.05) are highlighted in bold.