Table 1.
Antimicrobial susceptibility of predominant uropathogens among cases of culture-confirmed urinary tract infection in antenatal clinics at four tertiary public-sector hospitals in Gauteng Province, 2015–2019.
| Antibiotic | E. coli | K. pneumoniae | P. mirabilis | E. faecalis | S. agalactiae | All |
|---|---|---|---|---|---|---|
| n * (% [95% CI]) | ||||||
| Ciprofloxacin | 1626 (88% (86–89)) | 172 (96% (91–98)) | 157 (99% (96–100)) | 243 (96% (92–98)) | 16 (100% (79–100)) | 2483 (90% (89–91)) |
| Ampicillin/amoxicillin | 470 (24% (22–26)) | 0 (0% (0–1)) | 89 (51% (43–58)) | 612 (99% (99–100)) | 63 (100% (94–100)) | 1215 (38% (37–40)) |
| Trimethoprim/sulfamethoxazole | 742 (38% (36–40)) | 151 (75% (68–81)) | 85 (49% (41–56)) | 20 (37% (24–51)) | 16 (94% (71–100)) | 1234 (35% (33–36)) |
| Nitrofurantoin | 1827 (95% (94–96)) | 80 (40% (34–48)) | - | 301 (99% (97–100)) | - | 2374 (83% (82–85)) |
| Amoxicillin/clavulanic acid | 1594 (82% (81–84)) | 169 (85% (80–90)) | 165 (98% (94–99)) | - | - | 2034 (81% (79–82)) |
| Gentamicin | 1835 (93% (92–94)) | 178 (95% (90–97)) | 170 (94% (90–97)) | - | - | 2482 (93% (92–94)) |
| Cefepime | 1880 (95% (93–95)) | 185 (92% (87–95)) | 180 (99% (97–100)) | - | - | 2514 (94% (93–95)) |
| Cefotaxime/ceftriaxone | 1805 (93% (91–94)) | 177 (91% (86–95)) | 177 (99% (96–100)) | - | 84 (100% (96–100)) | 2489 (93% (92–94)) |
| Cefuroxime | 904 (86% (84–88)) | 165 (89% (83–92)) | 103 (99% (95–100)) | - | - | 1225 (85% (83–87)) |
| Cefazolin | 1122 (88% (86–90)) | 31 (97% (84–100)) | 86 (99% (94–100)) | - | - | 1367 (86% (84–88)) |
* Number of susceptible isolates, 95% CI = 95% confidence interval.