Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 10;12(6):895. doi: 10.3390/genes12060895

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Survival analysis for t(8;21)/RUNX1-RUNX1T1 (a,b), NK (c,d), and MLL/KMT2A-rearranged (e,f) patient samples based on the 50 most significant CpGs that separate the diagnostic samples of patients who later went on to relapse from those who did not. Panels (a,c,e) contain patients with a confirmed diagnostic subtype (diagnostic-known). Panels (b,d,f) contain diagnostic-known in addition DNA methylation predicted samples from the undefined group. In each panel, the heatmap (left), is ordered by hierarchical clustering. Samples along the x-axis are split into two groups color coded by high (red) or low (blue) overall methylation level. The numbers in the legend represent the fraction of patients who did not experience an event. Kaplan–Meier curve for relapse free survival analysis (upper right) and overall survival (lower right) of the two groups identified by clustering. The x-axis represents the time until event (months) and events are plotted on the y-axis.