Table 1.
General characteristics of the population enrolled.
| Authors | Type of Manuscript | AD (n) |
Controls (n) |
AD Patients | Controls | MMSE Score | Diagnostic Criteria | NOS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Age |
Females
(%) |
Mean Age |
Females
(%) |
AD | Controls | ||||||
| Kuriyama 1994 [23] | Case-control | 44 | 45 | 75.4 ± 6.0 | 37 (84.0) | 69.6 ± 8.9 | 27 (60.0) | NR | NR | DSM-III-R NINCDS-ADRDA |
8 |
| Smach 2012 [25] | Case-control | 173 | 150 | 75.0 ± 1.8 | 99 (57.2) | 71.1 ± 1.7 | 79 (52.6) | 15.0 ± 1.8 | 28.0 ± 0.32 ** | NINCDS-ADRDA | 8 |
| Uchida 2015 [24] | Case-control | 42 | 49 | 73.9 ± 7.4 | 32 (76.1) | 69.8 ± 12.4 | 16 (32.6) | 18.3 ± 5.8 | 28.8 ± 1.6 ** | DSM IV | 7 |
| Ya 2017 [26] | Case-control | 105 | 100 | 69.9 ± 4.4 | 45 (42.8) | 64.8 ± 5.8 | 50 (50) | 17.3 ± 5.5 | 26.8 ± 4.7 ** | DSM-IV-R NINCDS-ADRDA |
8 |
| Marksteiner 2015 [27] | Case-control | 33 | 23 | 81.0 ± 1.0 | 21 (63.6) | 71.0 ± 1.4 | 10 (43.4) | 20. 0± 0.8 | 29.0 ± 0.2 ** | NINCDS-ADRDA | 7 |
AD: Alzheimer’s disease; NR: Not reported; NINCDS-ADRDA: National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’s Disease and Related Disorders Association criteria; DSM: Diagnostic and Statistical Manual of Mental Disorders; NOS: Newcastle-Ottawa quality assessment scale. ** p < 0.001.