Table 2.
Multiple regression analysis with each subdomain as dependent variable.
| Dependent Variable | R 2 | Independent Variable | BA/Lobule | B | 95% CI | p Value |
|---|---|---|---|---|---|---|
| visuospatial/executive | 0.54 | IC31, MTG, CCN | 21 | 0.063 | 0.024 to 0.101 | 0.002 |
| IC49, MiFG, CCN | 10 | −0.060 | −0.112 to −0.009 | 0.024 | ||
| IC54, ITG, VIS | 37 | 0.050 | 0.019 to 0.082 | 0.003 | ||
| IC47, Cerebellum | VI, VII, VIII | 0.070 | 0.009 to 0.132 | 0.026 | ||
| IC56, SFG, CCN | 8 | −0.058 | −0.112 to −0.005 | 0.034 | ||
| naming | 0.39 | IC25, SFG, DMN | 8 | −0.026 | −0.043 to −0.010 | 0.003 |
| IC48, MiFG, CCN | 46 | 0.030 | 0.008 to 0.052 | 0.008 | ||
| IC14, Cuneus, VIS | 30 | −0.012 | −0.023 to −0.002 | 0.019 | ||
| attention | 0.86 | IC49, MiFG, CCN | 10 | −0.059 | −0.078 to −0.039 | <0.001 |
| IC71, STG, CCN | 38 | 0.056 | 0.036 to 0.075 | <0.001 | ||
| IC66, IFG, CCN | 46 | 0.043 | 0.026 to 0.059 | <0.001 | ||
| IC36, Cerebellum | VII | −0.027 | −0.043 to −0.011 | 0.002 | ||
| IC42, MiFG, SMN | 6 | 0.028 | 0.016 to 0.040 | <0.001 | ||
| IC15, MeFG, DMN | 11 | −0.031 | −0.042 to −0.020 | 0.005 | ||
| IC1, PrG, SMN | 4 | 0.012 | 0.004 to 0.020 | 0.005 | ||
| IC54, ITG, VIS | 37 | 0.020 | 0.008 to 0.032 | 0.002 | ||
| IC7, PoG, SMN | 3 | −0.025 | −0.042 to −0.008 | 0.005 | ||
| IC22, STG, CCN | 38 | −0.017 | −0.032 to −0.002 | 0.029 | ||
| language | 0.64 | IC24, Uncus, CCN | 20 | −0.119 | −0.159 to −0.079 | <0.001 |
| IC3, CN | 0.035 | 0.017 to 0.054 | 0.001 | |||
| IC17, MeFG, DMN | 8 | −0.046 | −0.067 to −0.024 | <0.001 | ||
| IC23, STG, AUD | 42 | −0.036 | −0.057 to −0.015 | 0.001 | ||
| IC62, MTG, VIS | 19 | 0.054 | 0.009 to 0.098 | 0.020 | ||
| IC35, MeFG, SMN | 6 | 0.023 | 0.002 to 0.044 | 0.034 | ||
| IC48, MiFG, CCN | 46 | 0.033 | 0.001 to 0.065 | 0.043 | ||
| abstraction | 0.10 | IC61, MiFG, CCN | 10 | −0.025 | −0.049 to 0.000 | 0.047 |
| delayed recall | NA | NA | NA | NA | NA | |
| orientation | 0.64 | IC49, MiFG, CCN | 10 | −0.050 | −0.068 to −0.031 | <0.001 |
| IC4, AC, DMN | 32 | −0.010 | −0.016 to −0.004 | 0.001 | ||
| IC50, STG, CCN | 38 | 0.034 | 0.016 to 0.052 | <0.001 | ||
| IC14, Cuneus, VIS | 30 | 0.011 | 0.002 to 0.021 | 0.024 | ||
| IC40, MeFG, SMN | 6 | −0.044 | −0.083 to −0.005 | 0.027 |
Abbreviations: AC, anterior cingulate; AG, angular gyrus; AUD, auditory network; BA, Brodmann area; auditory network; CCN, cognitive control network; CI, confidence interval; CN, caudate nucleus; DMN, default mode network; HY, Hoehn–Yahr stage; IFG, inferior frontal gyrus; ITG, inferior temporal gyrus; LED, levodopa equivalent dose; MeFG, medial frontal gyrus; MiFG, middle frontal gyrus; MTG, middle temporal gyrus; NA, not available; PoG, postcentral gyrus; PrG, precentral gyrus; SCN, subcortical network; SFG, superior frontal gyrus; SMN, somatomotor network; STG, superior temporal gyrus; VIS, visual network.