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Generation of ROS in electron transport chain (ETC). The ETC is located in the mitochondrial inner membrane (IM). Complex I and II supply electrons to coenzyme Q (CoQ; ubiquinone). Sequentially, electrons are transferred from CoQ to Complex III, cytochrome c (Cyt c) and Complex IV. Oxidative stress is generated during electron transfer. (Created with BioRender.com accessed on 29 March 2021).
