Table 2.
Univariable and Multivariable Regression Models for Radiotherapy Schedule Effect on Outcomes in Weighted and Unweighted Populations (HFRT versus BID [reference]).
| Outcome | Unweighted | Overlap Weighted | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariable | Multivariable | Univariable | Multivariable | |||||
| HR/OR (95% CI) | p-Value | HR/OR (95% CI) | p-Value | HR/OR (95% CI) | p-Value | HR/OR (95% CI) | p-Value | |
| OS | 0.84 (0.48–1.51) | 0.57 | 0.72 (0.36–1.40) | 0.32 | 1.16 (0.58–2.29) | 0.67 | 1.67 (0.70–3.95) | 0.25 |
| LRR risk | 0.86 (0.49–1.53) | 0.62 | 1.33 (0.64–2.75) | 0.44 | 1.29 (0.61–2.72) | 0.51 | 1.48 (0.62–3.54) | 0.38 |
| Thoracic Response | 3.89 (1.12–13.57) | 0.03 | 1.00 (0.22–4.64) | 1.00 | 1.00 (0.01–4.73) | 1.00 | 0.23 (0.02–2.23) | 0.21 |
Abbreviations: HFRT—hypofractionated radiotherapy, BID—twice-daily radiotherapy, CI—confidence interval, OS—overall survival, LRR—locoregional recurrence, OR—odds ratio, HR—hazard ratio.