Table 3.
Univariable and Multivariable Regression Models for Radiotherapy Schedule Effect on Grade 3+ Toxicity in Weighted and Unweighted Populations (HFRT versus BID [reference]).
| Toxicity | Unweighted | Overlap Weighted | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariable | Multivariable | Univariable | Multivariable | |||||
| OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | |
| Any Toxicity | 1.29 (0.14–0.36) | 0.52 | 1.31 (0.59–2.89) | 0.51 | 1.62 (0.58–4.53) | 0.36 | 1.67 (0.59–4.72) | 0.33 |
| Pulmonary | 1.29 (0.39–4.27) | 0.68 | 1.16 (0.31–4.30) | 0.82 | 1.06 (0.25–4.50) | 0.93 | 1.14 (0.32–4.10) | 0.84 |
| Esophageal | 1.15 (0.47–2.84) | 0.76 | 1.19 (0.47–3.02) | 0.72 | 1.38 (0.38–5.00) | 0.63 | 1.41 (0.36–5.51) | 0.62 |
Abbreviations: HFRT—hypofractionated radiotherapy, BID—twice daily radiotherapy, CI—confidence interval, OR—odds ratio.