Table 6.

Statistical comparisons between mRNA relative expressions in control and pheromone groups on Day 0 (D0) and D8. Levels of expression in controls are shown in the second column (high, amplification around 17–26 cycle quantification (Cq); moderate, 26–31 Cq; low, >31 Cq). p-values are presented in other columns. As the data were not paired and non-normally distributed, group means were compared using the Wilcoxon signed rank test (exact). ** p < 0.010. In bold, significant p-values and p-values nearly significant; ns, not significant; SEM, standard error of the mean.

Messenger RNAs	Levels of Expression (Controls)	D0			D8
		mRNA Relative Expressions ± SEM		Pheromone vs. Control	mRNA Relative Expressions ± SEM		Pheromone vs. Control
		Control (N = 15)	Pheromone (N = 18)		Control (N = 15)	Pheromone (N = 18)
CCL20	low	13.87 ± 4.13	20.72 ± 4.84	ns	12.38 ± 1.79	18.24 ± 3.26	ns
CXCL6	moderate	5.56 ± 1.64	14.77 ± 6.74	ns	5.91 ± 1.32	8.84 ± 2.18	ns
FOXP3	moderate	6.3 ± 0.9	5.85 ± 0.77	ns	4.86 ± 0.71	4.39 ± 0.71	ns
GATA-3	high	6.32 ± 0.92	8.15 ± 1.26	ns	4.72 ± 0.51	4.7 ± 0.62	ns
IFNɣ	low	18.44 ± 4.49	45.86 ± 16.27	ns	17.93 ± 3.92	37.83 ± 11.35	ns
IL10	moderate	4.15 ± 0.70	4.57 ± 1.11	ns	2.68 ± 0.51	2.76 ± 0.25	ns
IL12 p40	moderate	213.23 ± 40.59	155.05 ± 47.51	0.073	87.49 ± 22.68	82.28 ± 15.69	ns
IL17A	low	22.06 ± 10.57	34.94 ± 15.77	ns	57.53 ± 30.78	43.67 ± 14.51	ns
IL4	low	6.28 ± 4.00	0.81 ± 0.45	ns	1.13 ± 0.71	3.34 ± 2.13	ns
IL6	low	11.32 ± 4.68	11.15 ± 3.88	ns	11.33 ± 2.21	5.55 ± 1.78	0.055
IL8	moderate	231.45 ± 82.35	321.85 ± 62.56	0.053	178.25 ± 95.58	330.61 ± 104.61	0.004 **
RORɣ	moderate	6.25 ± 0.86	5.32 ± 0.46	ns	4.86 ± 0.64	5.03 ± 0.64	ns
TBX21	moderate	8.51 ± 1.47	9.33 ± 1.66	ns	4.78 ± 0.74	3.8 ± 0.60	ns
TGFß	high	3.36 ± 0.38	3.12 ± 0.32	ns	2.78 ± 0.37	3.32 ± 0.18	ns