. 2021 Jun 10;26(12):3542. doi: 10.3390/molecules26123542

Table 4.

Lipophilicity of curcumin and hydrocurcumin analogs in two different biphasic (octanol—water: logP_oct/w and toluene—water: logP_tol/w) systems. Data represent average ± S.E.M from five parallel experiments.

Compound	logP_oct/w	logP_tol/w	ΔlogP_{oct_tol}
4HC	2.58 ± 0.07	2.27 ± 0.05	0.31
6HC	2.15 ± 0.01	1.69 ± 0.03	0.46
8HC	2.30 ± 0.02	1.55 ± 0.14	0.75