Table 1.
Demographic and baseline characteristics in CRC patients with low and high TAM infiltration groups
| Characteristicsa | CD163+ TAMs ≤115 (n = 105) | CD163+ TAMs > 115 (n = 104) | P valueb |
|---|---|---|---|
| Age (years) | 0.607 | ||
| ≤ 60 | 42 (40.0%) | 38 (36.5%) | |
| > 60 | 63 (60.0%) | 66 (63.5%) | |
| Sex | 0.216 | ||
| Male | 62 (59.0%) | 70 (67.3%) | |
| Female | 43 (41.0%) | 34 (32.7%) | |
| Location | 0.427 | ||
| Rectum | 75 (71.4%) | 69 (66.3%) | |
| Colon | 30 (28.6%) | 35 (33.7%) | |
| TNM stage | 0.599 | ||
| I | 71 (67.6%) | 68 (65.4%) | |
| II | 27 (25.7%) | 25 (24.0%) | |
| III | 7 (6.7%) | 11 (10.6%) | |
| Differentiation | 0.081 | ||
| Poorly | 0 (0.0%) | 3 (2.9%) | |
| Moderately | 103 (98.1%) | 101 (97.1%) | |
| Well | 2 (1.9%) | 0 (0.0%) | |
| Examined lymph nodes | 0.020 | ||
| ≤ 12 | 18 (17.1%) | 7 (6.7%) | |
| > 12 | 87 (82.9%) | 97 (93.3%) | |
| CEA | 0.721 | ||
| < 5 | 79 (75.2%) | 76 (73.1%) | |
| ≥ 5 | 26 (24.8%) | 28 (26.9%) | |
| CA199 | 0.300 | ||
| < 37 | 102 (97.1%) | 98 (94.2%) | |
| ≥ 37 | 3 (2.9%) | 6 (5.8%) |
TAMs, tumor-associated macrophages; TNM, tumor node metastasis; CEA, carcinoembryonic antigen; CA, carbohydrate antigen
an (%)
bChi-square test