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Scheme of the DARPin library design. (A) Libraries are composed of capping N- and C-terminus and a varying number of modules (n). The ankyrin repeat module consists of 33 amino acids. The red color highlights the randomized surface for potential target interaction (Figure adopted according to [53]. (B) Structure of NI3C (PDB ID: 2QYJ) as a representative example rainbow colored from the N- to the C-terminus [5].
