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A proposed behavior of oxidized lipoproteins in atherosclerotic lesions and circulation. When LDL is oxidatively modified, HDL can interact with oxLDL to attenuate oxidative modification of LDL; in turn, HDL is modified to form oxHDL. A part of oxHDL may be associated with oxLDL. These oxidatively modified lipoproteins accumulate in vulnerable plaque and are released into the circulation when the plaque ruptures.
