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. 2021 Jun 9;26(12):3513. doi: 10.3390/molecules26123513

Table 3.

Subgroup analyses of blood glucose levels in chemical- and diet-induced DM rodent models.

DM Type Subgroups Effect Size Heterogeneity (I2) Test of Group Difference (p)
No. of Studies g 95% CI p-Value
Chemical-induced Sex
Males 20 −5.78 −7.12 −4.44 <0.001 86.71 0.06
Females 2 −0.93 −4.74 2.87 0.63 31.22
Both 6 −4.64 −7.11 −2.16 <0.001 95.15
Parts
Leaves 21 −4.46 −5.74 −3.17 <0.001 89.79 0.15
Seeds 3 −7.40 −11.06 −3.74 <0.001 96.35
Others 5 −6.76 −9.61 −3.90 <0.001 87.93
Blood sample
Plasma 4 −5.74 −8.88 −2.60 <0.001 90.90 0.71
Serum 6 −6.37 −8.98 −3.66 <0.001 91.36
Whole blood 17 −5.05 −6.60 −3.49 <0.001 90.87
Diet-induced Sex
Males 9 −1.73 −2.77 −0.68 0.001 86.98 0.98
Females 2 −1.70 −3.68 0.28 0.09 59.05
Parts
Leaves 7 −2.04 −3.32 −0.76 0.002 90.16 0.63
Seeds 3 −1.11 −2.75 0.53 0.18 0.00
Others 1 −2.32 −5.30 0.65 0.13 0.00
Blood sample
Serum 4 −3.15 −5.06 −1.24 0.001 94.47 0.10
Whole blood 7 −1.29 −2.36 −0.25 0.02 47.90