Figure 2.

Mitochondrial fatty acid oxidation (FAO) rates (blue bars) and effects of resveratrol (RSV) (red bars) in fibroblasts of ASD patients and healthy control individuals. Figure shows participants with autism spectrum disorder (ASD) that also have acyl-carnitine (AC) elevations (ASD w-AC) and participants with ASD without AC elevations (ASD w/o-AC) as well as control participants. Under basal conditions, the β-oxidation flux (nmol ³HFA/h/mg protein) measured in fibroblasts of patients with ASD w-AC were significantly decreased compared with the ASD w/o-AC. RSV significantly increased mtFAO values in all the study groups. The results are means (±SD) of three different experiments. * p < 0.05.