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. 2021 Jun 3;13(6):830. doi: 10.3390/pharmaceutics13060830

Scheme 1.

Scheme 1

(A) Metformin and (B) amino acid sequence and NMR structure of hIAPP (PDB: 2KB8). The side chains of Cys [2] and Cys [7] are shown in yellow to illustrate the disulfide bond.