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. 2021 Jun 9;11(6):860. doi: 10.3390/biom11060860

Figure 3.

Figure 3

Downregulation of CDK5 inhibits STAT3 activation. (A) Protein expression level of pSTAT3 (ser727) and total STAT3 proteins under GDNF treatment for 30 min, 1.5 h and 6 h, respectively. (B) Protein expression level of pSTAT3 (ser727) and total STAT3 proteins under the treatment of GDNF, and GDNF + RV for 1.5 h. RV: Roscovitine, a pan CDK inhibitor.