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. 2021 Jun 10;9(6):630. doi: 10.3390/vaccines9060630

Figure 3.

Figure 3

Humoral immune responses in vaccinated and challenged mice. (A) EBOV GP-specific IgG was assessed in serum samples from mice on day 0 (n = 4; 28 days after vaccination), day 4 (n = 4) and day 42 (all survivors). Geometric mean and SD are depicted. Statistical significance is indicated, p < 0.05 (*). (B) Neutralizing activity in the serum of vaccinated mice (day 0, n = 4 per group) and (C) challenge survivors (day 42; n = 6 for VSV-EBOV and VSV-EBOV∆MLD or n = 1 for VSV-EBOV∆GC∆MLD) was determined using the EBOV trVLP system expressing eGFP. Mean and SD are depicted.