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Temporal milestones of antibody–drug conjugates currently approved for the treatment of BC. Abbreviations: HER2, human epidermal growth factor receptor 2; T-DM1, trastuzumab emtansine; T-Dxd, trastuzumab deruxtecan; EMA, European Medicines Agency; FDA, Food and Drug Administration; 1MBC, metastatic breast cancer; 2EBC, early breast cancer; 3ABC, advanced breast cancer; mTNBC, metastatic triple-negative breast cancer.
