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Graphical illustration of the mAChR M1 crystal structure PDB:5CXV [54] using Mol* [62]. The approximal location of the orthosteric binding site and the allosteric binding sites are highlighted. The receptor structure contains the co-crystallized orthosteric antagonist tiotropium, which is displayed in ‘ball and stick’ style. In the side view the protein is displayed as cartoon and in the top view it is displayed as Gaussian surface.
