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. 2021 Jun 7;11(6):530. doi: 10.3390/life11060530

Figure 6.

Figure 6

SS-1 reduced LPS-induced surface costimulatory markers and cytokine production in BMDCs. (A) BMDCs from naïve mice were stimulated with LPS and treated with or without SS-1 at the indicated concentrations followed by evaluation of costimulatory marker expression (CD80 and CD86). (B) The mean fluorescence intensity (MFI) of cellular marker molecule expression (CD80 and CD86) was quantified after gating on CD11c+ cells. (C) IL-12 and IL-23 cytokine production was detected by ELISA. Data are means ± SEMs (n = 5). The data presented are representative of three independent experiments with similar results. * p < 0.05, *** p < 0.001 versus LPS + water-treated control.