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. 2021 Jun 6;10(6):1405. doi: 10.3390/cells10061405

Figure 3.

Figure 3

The effect of hydroquinone (HQ 10 μM, 200 μM; 18 h) on the levels of NLRP3 in cell lysate (A) and medium (B) samples in IL-1α-primed ARPE-19 cell cultures. Results (A) were normalized to the total protein level. Absorbance values in (A) were 0.263–0.507 in the control, 0.548–1.516 in the IL-1α, 0.416–0.862 in the IL-1α + HQ 10 μM, and 4.492–9.375 in the IL-1α + HQ 200 μM group. NLRP3 concentrations in medium samples (B) were 0.590–2.054 ng/mL in the control, 11.81–161.453 ng/mL in the IL-1α, 10.345–28.244 ng/mL in the IL-1α + HQ 10 μM, and 1.268–6.303 ng/mL in the IL-1α + HQ 200 μM group. Data were combined from three independent experiments with two (A) or three (B) parallel samples per group in each experiment. Results are shown as mean ± SEM. *** p < 0.001, **** p < 0.0001, ns—not significant, Mann-Whitney U-test.