Figure 4.

The effect of 200 μM hydroquinone (HQ; 18 h) on the cleaved caspase-1 (p20) levels detected from cell lysate (A) samples and the effect of caspase-1 inhibitor (casp.-1 inhib.; 20 μM in DMSO 0.22% v/v) on the hydroquinone-induced IL-18 release (B) in IL-1α-primed ARPE-19 cells. Absorbance values in (A) were 0.225–0.288 in the control, 0.259–0.379 in the IL-1α, and 0.149–0.161 in the IL-1α + HQ 200 μM group. Data were combined from two (A) or one (B) independent experiments with two (A) or four (B) parallel samples per group. Results are shown as mean ± SEM. * p < 0.05, ns—not significant, Mann-Whitney U-test.