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. 2021 Jun 6;10(6):1405. doi: 10.3390/cells10061405

Figure 5.

Figure 5

The effect of 200 μM hydroquinone (HQ; 18 h) on the IL-18 secretion (A) and on the intracellular NLRP3 level (B) in unprimed ARPE-19 cells. An untreated control group was used as the control for hydroquinone treatment. IL-18 concentrations in medium samples (A) were 4.552–10.556 pg/mL in the control and 32.132–123.617 pg/mL in the HQ 200 μM group. Absorbance values in (B) were 0.443–0.563 in the control and 0.345–0.579 in the HQ 200 μM group. Data were combined from two independent experiments containing four (A) or two (B) parallel samples per group. Results are shown as mean ± SEM. *** p < 0.001, ns—not significant, Mann-Whitney U-test.