Table 2.
Species (No. of Isolates) | Antifungal | Range | MIC 50 mcg/mL | MIC 90 mcg/mL | Non-Susceptible (%) |
---|---|---|---|---|---|
C. parapsilosis (n = 42) | Amphotericin | 0.25–1 | 0.5 | 1 | 0 |
Anidulafungin | 0.25–2 | 1 | 2 | 0 | |
Fluconazole | 0.125–2 | 0.25 | 2 | 2.4 | |
Voriconazole | 0.03–0.25 | 0.03 | 0.03 | 0 | |
C. albicans (n = 40) | Amphotericin | 0.25–1 | 1 | 1 | 0 |
Anidulafungin | 0.03–1 | 0.25 | 0.25 | 2.5 | |
Fluconazole | 0.125–4 | 0.25 | 0.25 | 0 | |
Voriconazole | 0.03–0.06 | 0.03 | 0.03 | 0 | |
C. tropicalis (n = 19) | Amphotericin | 0.25–1 | 0.5 | 1 | 0 |
Anidulafungin | 0.03–0.5 | 0.125 | 0.5 | 0 | |
Fluconazole | 0.125–0.5 | 0.25 | 0.5 | 0 | |
Voriconazole | 0.03–0.06 | 0.03 | 0.06 | 0 | |
C. glabrata (n = 5) | Amphotericin | 0.5–1 | 1 | 1 | 0 |
Anidulafungin | 0.03–0.25 | 0.125 | 0.25 | 40 | |
Fluconazole | 2–8 | 4 | 8 | 100 | |
Voriconazole | 0.06–0.5 | 0.125 | 0.5 | N.D. | |
Other species (n = 3) | Amphotericin | 0.25–0.5 | 0.5 | 0.5 | 0 |
Anidulafungin | 0.06–1 | 1 | 1 | 66 * | |
Fluconazole | 0.125–2 | 0.125 | 2 | 0 | |
Voriconazole | 0.03–0.06 | 0.03 | 0.06 | N.D |
* With C. guillermondii break points. N.D. = Not defined.