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The values of log (GCP/PFU) for the virus samples of four TBEV strains: EK-328 (blue), Absettarov (Abs, green), Sofjin (Sof, yellow) and 256 (orange) after the reproduction (a) in PEK cell culture (CF) and in ICR suckling mouse brains (MB) after i/c inoculation. (b) GCP/PFU ratio of Absettarov TBEV strain after 7 days in Ixodes ricinus ticks. The experiment was carried out in 3–5 biological replicates. Error bars indicate SD. * p < 0.05; ** p < 0.01 obtained by Mann-Whitney test.
