Table 2.
TBEV Strain | Passage History * | LD50 | PFU | GCP |
---|---|---|---|---|
Far Eastern Subtype | ||||
Sofjin KGG | P1M2 | 100 | 130,000 | 350,000 |
Siberian Subtype | ||||
Vasilchenko | хМ2V1 | 100 | 5,000 | 60,000 |
EK-328 | М6P1М4 | 100 | 1000 | |
European Subtype | ||||
Absettarov | Mx | 100 | 10,000 | 1,000,000 |
* M—mouse brain passage (Mx—unidentified number of early passages before the virus was obtained by the laboratory); P—passage in PEK cell culture, V—passage in Vero cell culture.