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. 2021 Jun 8;13(6):851. doi: 10.3390/pharmaceutics13060851

Figure 2.

Figure 2

Log-reduction values obtained using time-kill assays for PRE (MIC/2), Zn (II) (MIC/2), and PRE/Zn (II) (MIC/2 + MIC/2) in combination against M. luteus. All data are represented as mean ± SEM (n = 3). Note: synergistic activity at 240 min, showing a 6.88 ± 1.02 log reduction for PRE/Zn (II), which was significantly greater than the 1.83 ± 0.24 log reduction for PRE and the 3.4 ± 0.08 log reduction for Zn (II); statistical significance indicated at *** p < 0.001 and **** p < 0.0001 between treatment groups.