Table 3.
Odds ratios (ORs) and 95% confidence intervals (CIs) for the risk of poor functional outcome (mRS ≥ 3) after 3 months and 2 years in the lowest quintile of acute serum IGF-II compared to the four higher IGF-II quintiles in the total stroke population.
| Total Stroke Population | Quintile 1 | Quintile 2–5 | p-Value | n |
|---|---|---|---|---|
| 3-month mRS | ||||
| Crude | 2.30 (1.39–3.82) | 1.0 referent | 0.001 | 463 |
| Multivariate model A | 2.24 (1.33–3.79) | 1.0 referent | 0.002 | 463 |
| Multivariate model B | 1.95 (1.10–3.45) | 1.0 referent | 0.023 | 446 |
| Multivariate model C | 0.99 (0.46–2.13) | 1.0 referent | 0.98 | 446 |
| Multivariate model D | 0.71 (0.30–1.64) | 1.0 referent | 0.42 | 445 |
| 2-year mRS | ||||
| Crude | 1.93 (1.17–3.18) | 1.0 referent | 0.010 | 485 |
| Multivariate model A | 1.76 (1.04–2.95) | 1.0 referent | 0.034 | 485 |
| Multivariate model B | 1.59 (0.90–2.80) | 1.0 referent | 0.11 | 463 |
| Multivariate model C | 0.90 (0.46–1.77) | 1.0 referent | 0.76 | 463 |
| Multivariate model D | 0.79 (0.39–1.58) | 1.0 referent | 0.50 | 462 |
ORs and 95% CIs were calculated using binary logistic regression. Data are shown as n and OR (95% CI). Model A: adjustment for age and sex. Model B: age, sex, and cardiovascular risk factors (BMI, hypertension, LDL, smoking, and diabetes). Model C: age, sex, cardiovascular risk factors, and stroke severity. Model D: age, sex, cardiovascular risk factors, stroke severity, and hsCRP. LDL, low-density lipoprotein; BMI, body mass index; hsCRP, high-sensitivity C-reactive protein.