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. 2021 Jun 9;10(6):1331. doi: 10.3390/foods10061331

Figure 5.

Figure 5

Protective effects of XN against AFB1-induced cytotoxicity. The effects of XN (0.01, 0.1, 1 and 10 µM), AFB1 (10, 20 and 30 µM), and the AFB1 (30 µM)—XN (0.01, 0.1, 1 and 10 µM) combinations on the viability of HepG2 cells after 24 h of exposure, presented as a percentage of the solvent control (0; 1% DMSO—upper dashed line). NC is the negative control (growth medium). PC is the positive control—ET (25 μg/mL). The lower red dashed line represents the average reduction in cell viability by AFB1 (30 µM). The asterisks (*) denote statistically significant difference (ANOVA and Dunnet’s multiple comparison test) between the solvent control and the AFB1, XN, and their combinations exposed cells (* p ≤ 0.05; *** p ≤ 0.001). The red dots (•) denote a statistically significant difference (ANOVA and Dunnet’s multiple comparison test) between the cells exposed to AFB1 (30 µM) and to the AFB1-XN combinations (•• p ≤ 0.01).