Table 3.

PBPK models developed with antimicrobial drugs in special populations.

Reference	Patient Population	Antimicrobial	Route of Administration
Balbas-Martinez et al. [103]	Children with complicated urinary tract infection	Ciprofloxacin	Oral/intravenous
Schlender et al. [104]	Pediatric/adult/geriatric	Ciprofloxacin	Oral/intravenous
Montanha et al. [105]	Bariatric patients	Amoxicillin	Oral tablet/suspension
Thémans et al. [106]	Critical/non critical/obese	Meropenem	Intravenous
Cordes et al. [107]	Patients with tuberculosis	Isoniazid	Oral
Hornik et al. [108]	Pediatric	Clindamycin	Intravenous
Rimmler et al. [109]	Perioperative patients	Cefuroxime	Intravenous
Joyner et al. [110]	Patients with different body mass indexes	Ertapenem	Intravenous
Tod et al. [111]	Patients with hemorrhagic shock followed by fluid resuscitation	Amoxicillin-clavulanate	Intravenous