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. 2021 Jun 7;10(6):928. doi: 10.3390/antiox10060928

Figure 2.

Figure 2

The dose effect of green tea extracts catechins on the morphologic alteration in SARS-CoV-infected Vero E6 cells (A). Vero E6 cells were treated with different concentrations of catechins, and the cell morphology was determined at 48 h post-infection. Vero E6 cells were normally expressed in the medium with catechins (6.25 mg–195 μg) treatment, however, the infected Vero E6 cells without catechins treatment died and floated in the medium. The positive panel shows cells infected by SARS-CoV without catechins treatment; while the negative panel shows cells without virus infection. The dose effect of catechins on inhibiting viral antigen synthesis in SARS-CoV-infected Vero E6 cells (B). Vero E6 cells were treated with several concentrations of catechins, and an IFA was examined at 48 h post-infection. Viral antigen synthesis was partial blocked at 98 μg/mL of catechins and completely blocked > 195 μg/mL of catechins. The same dose of 195 μg/mL tannin or procyanidin could not inhibit viral synthesis. The positive panel displays the cells infected by SARS-CoV without catechins treatment; whereas the negative panel displays the cells without SARS-CoV infection. T, tannin; P, procyanidin.