Table 1.
Demographics and clinical characteristics of the study cohort.
| Baseline Characteristics | IBS (n = 40) | Healthy (n = 18) | p Value |
|---|---|---|---|
| Sex (F:M) | 31:9 | 9:9 | 0.04 |
| Age, years † | 52 (24–70) | 26 (19–54) | <0.001 |
| IBS subtypes IBS-C:IBS-D:IBS-nonCnonD | 15:11:14 | N/A | |
| IBS-SSS ‡ | 236 (174–327) | 11 (0–20) | <0.001 |
| Mild:moderate:severe § | 10:17:13 | N/A | |
| HADS total score ¶ | 9.9 ± 5.9 | 6.8 ± 3.9 | <0.05 |
| Anxiety:no anxiety φ | 14:17 | 3:15 | 0.04 |
| Depression:no depression φ | 3:28 | 0:18 | 0.17 |
Note: Abbreviations: N/A, not applicable; IBS-C, IBS with constipation; IBS-D, IBS with diarrhoea; IBS-nonCnonD, mixed-type IBS and unclassified IBS; IBS-SSS, IBS Severity Scoring System; HADS, Hospital Anxiety and Depression Scale. † Data shown as median (min–max). ‡ Data shown as median (interquartile range). § Based on IBS-SSS. ¶ Data shown as mean ±SD. φ Based on HADS.