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. 2021 Jun 10;10(6):1462. doi: 10.3390/cells10061462

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Characterization of chondrocyte subtypes. (A) Feature plots showing the expression of key chondrocyte markers. Blue: high expression, grey: low expression. (B) UMAP plots of various chondrocyte subtypes in mouse knee joints. Colors indicate clusters of various cell types with distinct gene expression profiles. (C) Heatmap showing the scaled expression of top genes differentially expressed in each cluster. (D) Violin plots showing the expression of selected markers of various chondrocyte subtypes. (E) Monocle pseudotime trajectory colored based on chondrocyte clusters in (A). (F) Expression of chondrocyte subtype markers on a pseudotime scale (colored based on clusters in (A)).