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. 2021 Jun 10;10(6):1462. doi: 10.3390/cells10061462

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Functional characterization of chondrocyte subtypes. (A) Enriched ontologies for each chondrocyte subtype. Circle size indicates the number of genes associated with each category. (B) Circos plot showing overlap between genes enriched (>1.25-fold) in each cluster compared to all other clusters. The purple curves link identical genes. (C) Feature plots showing the expression of Matn3, Cytl1, Spp1, and Chil1. (D) Protein-level expression of Matn3 (red) and Cytl1 (green). (E) Protein-level expression of Chil1/CHI3L1 (red). (F) Protein-level expression of Spp1 (red). DAPI (blue); C: cartilage; B: bone; M: meniscus.