Table 2.
Published values of in situ Gambierdiscus toxin quota. Toxin measurements determined by mouse bioassay (MBA) were originally compiled by Litaker et al. [15] and were standardized prior to conversion to toxin quotas, assuming one mouse unit = 18 ng of CTX3C and 72 ng of C-CTX-1 for Pacific and Caribbean samples, respectively [39,40].
| Location | Cell Toxin Quota (pg CTX eq. Cell−1) |
Method | N | Reference | |
|---|---|---|---|---|---|
| Range | Mean | ||||
| Northwest Hawaiian Is., Hawaii |
- | 24 | 1 MBA | 1 | [43] |
| Papara, Tahiti, French Polynesia | 0.09–3.60 | 0.25 ± 0.18 | 1 MBA | 34 | [23] |
| Rapa Island, French Polynesia | 0.5–13.5 | - | 2 RBA | 4 | [44] |
| Gambier Islands, French Polynesia |
0.03–1.00 | 0.15 ± 0.26 | 1 MBA | 6 | [45] |
| Hitiaa Reef, Tahiti, French Polynesia | 0.05–1.35 | 0.16 ± 0.20 | 1 MBA | 10 | [46] |
| Gambier Islands, French Polynesia |
0.96–1.42 | 1.15 ± 0.32 | 1 MBA | 2 | [47] |
| Platypus Bay, Australia | - | 0.23 | 1 MBA | 1 | [48] |
| Nuku Hiva, French Polynesia |
0.85–3.90 | 2.38 ± 2.15 | 2 RBA | [49] | |
| Rapa, French Polynesia | - | 0.03 ± 0.004 | 3 N2a | 1 | [50] |
| ^ St. Thomas, US Virgin Islands | 1.14–5.14 | 1.54 ± 0.94 | 1 MBA | 3 | [51] |
| ^ St. Thomas, US Virgin Islands | 0.00–12.62 | 0.56 ± 1.75 | 3 N2a | 125 | This Study |
1 Mouse Bioassay (MBA); 2 Radioligand Receptor Binding Assay (RBA), 3 In vitro mouse neuroblastoma MTT based assay (N2a); 4 sample number (N). ^ Caribbean Region.