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. 2021 Jun 10;11(6):1071. doi: 10.3390/diagnostics11061071

Table 1.

Summary of Related Works.

References Deep Learning Model Brain Region Contribution Limitations
[30] VGG 19 Gray Matter Model provided clear distinction between EMCI and LMC Low classification accuracy for intermediate stages
[22] CNN with Ensemble Learning Whole brain Baseline Low classification accuracy for MCIc vs. MCI nc
[31] 3D Convolutional LSTM Whole brain Accuracy was improved Prodromal stages of AD were not considered
[25] 3D CNN Whole brain Model learned temporal and spatial features Model was designed for a specific size of fMRI volume
[28] CNN with residual connection Hippocampus Baseline N/A
[29] Inception-ResNet V2 Whole brain Based on various age groups, the model was able to extrapolate the prediction of different phases Model did not address the problem of EMCI vs. NC binary classification
[33] CNN Whole brain Model recognized pattern of brain functional changes associated with AD progression Intermediate stages of AD were not considered
[36] AlexNet Whole brain Model classified all stages of AD Low binary classification accuracy
[37] VGG16 Whole brain Model was able to extract useful features the binary classification tasks High computational complexity