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Depiction of tumor mass localized in the colon. Zoomed-in illustration of the tumor microenvironment (TME), including tumor cells, stromal cells and immune cells. Tumor cells with proximity to the blood vessel are marked as oxygenated while distant cells are referred to as hypoxic. The complex networking contains different types of cells, an extracellular matrix (ECM) and molecules such as cytokines, chemokines and microvesicles (such as exosomes).
