. 2021 Jun 10;10(12):2574. doi: 10.3390/jcm10122574

Table 4.

Correlation between vascular density and clinical parameters.

Vascular Desity		Age ^a	Sex ^b	DM ^b	HBP ^b	CVD ^b	BCVA ^a
Disc total VD	Coefficient	−0.076	−0.076	−0.038	0.090	0.043	−0.147 *
Disc total VD	p-value	0.274	0.274	0.582	0.196	0.533	0.034
Disc small and medium VD	Coefficient	−0.305 *	−0.058	−0.204 *	−0.111	−0.019	−0.237 *
Disc small and medium VD	p-value	0.000	0.409	0.003	0.111	0.790	0.001
Disc Large VD	Coefficient	0.163 *	0.023	0.096	0.135	0.041	0.159 *
Disc Large VD	p-value	0.019	0.738	0.171	0.054	0.558	0.023
Peripapillary VD	Coefficient	−0.206 *	0.125	−0.112	−0.018	0.022	−0.311 *
Peripapillary VD	p-value	0.003	0.073	0.110	0.799	0.757	0.000
Peripapillary VD ST	Coefficient	−0.198 *	0.102	−0.161 *	−0.070	−0.042	−0.270 *
Peripapillary VD ST	p-value	0.004	0.146	0.021	0.320	0.552	0.000
Peripapillary VD SN	Coefficient	−0.166 *	0.038	−0.010	0.134	0.001	−0.319 *
Peripapillary VD SN	p-value	0.017	0.585	0.884	0.055	0.989	0.000
Peripapillary VD IN	Coefficient	−0.146 *	0.081	−0.087	−0.053	0.069	−0.244 *
Peripapillary VD IN	p-value	0.037	0.247	0.212	0.453	0.326	0.000
Peripapillary VD IT	Coefficient	−0.145 *	0.139 *	−0.128	−0.128	0.043	−0.204 *
Peripapillary VD IT	p-value	0.038	0.047	0.066	0.068	0.540	0.003
Vascular Desity		Refractive Error ^a	Axial Length ^a	IOP ^a	RNFL Thickness ^a	VF Mean Deviation ^a	Disc Hemorrhage ^b
Disc total VD	Coefficient	0.176 *	−0.211 *	−0.088	0.105	0.183 *	0.016
Disc total VD	p-value	0.011	0.002	0.207	0.132	0.008	0.821
Disc small and medium VD	Coefficient	−0.218 *	0.169 *	−0.047	−0.005	0.109	0.069
Disc small and medium VD	p-value	0.002	0.015	0.505	0.940	0.118	0.326
Disc Large VD	Coefficient	0.236 *	−0.242 *	0.031	0.025	−0.028	−0.060
Disc Large VD	p-value	0.001	0.000	0.654	0.716	0.695	0.393
Peripapillary VD	Coefficient	0.034	−0.065	−0.039	0.247 *	0.277 *	0.027
Peripapillary VD	p-value	0.630	0.356	0.581	0.000	0.000	0.697
Peripapillary VD ST	Coefficient	−0.015	−0.030	−0.044	0.114	0.234 *	0.116
Peripapillary VD ST	p-value	0.832	0.668	0.531	0.104	0.001	0.096
Peripapillary VD SN	Coefficient	0.032	−0.037	−0.007	0.254 *	0.162 *	0.057
Peripapillary VD SN	p-value	0.646	0.596	0.922	0.000	0.020	0.414
Peripapillary VD IN	Coefficient	0.054	−0.049	−0.029	0.176 *	0.233 *	−0.016
Peripapillary VD IN	p-value	0.437	0.486	0.682	0.011	0.001	0.825
Peripapillary VD IT	Coefficient	0.086	−0.092	−0.047	0.208 *	0.256 *	−0.076
Peripapillary VD IT	p-value	0.221	0.189	0.505	0.003	0.000	0.275

DM: diabetes mellitus; HTN: hypertension; CVD: cardio- or cerebrovascular disease; BCVA: best-corrected visual acuity; IOP: intraocular pressure; RNFL: retinal nerve fiber layer; VF: visual field; VD: vascular density; ST: superotemporal; SN: superonasal; IN: inferonasal; IT: inferotemporal. ^a Spearman rank correlation. ^b Logistic regression. * P < 0.01 (two-tailed).