Figure 6.

EGCG, TSA, and TFDG interfered with the interaction between ACE2 and RBD. The indicated concentrations of each compound as well as a mixture of 40 µM TSA, 75 µM TF3G, 35 µM TF3′G, and 60 µM TFDG (cocktail) were subjected to a neutralizing assay using a SARS-CoV-2 Surrogate Virus Neutralization Test Kit (GenScript, Piscataway, NJ, USA) as described in the Materials and Methods section. % Inhibition for each sample is shown. Values are means ± S.D. (n = 3 (a) or 4 (b)). *** p < 0.001 vs. Negative control by Tukey’s multiple comparison test.