Skip to main content
. 2021 Jun 11;10(6):1190. doi: 10.3390/plants10061190

Figure 3.

Figure 3

Acute effects of (A) sitagliptin and (B) hot-water extract of A. arabica bark on DPP-IV enzyme activity in vitro, (C) glucose tolerance, (D) plasma insulin and (E) plasma DPP-IV in high-fat-fed rats. Parameters were measured prior to and after oral administration of glucose alone (18 mmol/kg body weight, control) or with simultaneous A. arabica extract (250 mg/5 mL/kg body weight). Established DPP-IV inhibitors, sitagliptin and vildagliptin, were used as positive controls. Values are the mean ± SEM, n = 3 for DPP-IV enzyme activity in vitro and n = 6 for glucose tolerance, plasma insulin and DPP-IV in vivo. * p < 0.05, ** p < 0.01 and *** p < 0.001, compared to normal control and Δ p < 0.05, ΔΔ p < 0.01 and ΔΔΔ p < 0.001 compared to high-fat-fed control.