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. 2021 Jun 11;10(6):1190. doi: 10.3390/plants10061190

Figure 9.

Figure 9

Insulin-releasing effects of (A) Quercetin and (B) Kaempferol, (C) membrane potential and (D) intracellular calcium from BRIN-BD11 cells, (E,G) glucose tolerance and (F,H) plasma insulin. Mice were fasted for 12 h and administered glucose (18 mmol/kg body weight) by oral gavage with or without (E,F) simultaneous quercetin (100 mg/kg b.w.) and (G,H) kaempferol (70 mg/kg b.w.). Values are the mean ± SEM for n = 8 for insulin release, n = 6 for membrane potential, intracellular calcium, glucose tolerance and plasma insulin. * p < 0.05, ** p < 0.01 and *** p < 0.001 compared to control.