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. 2021 Jun 11;10(6):1468. doi: 10.3390/cells10061468

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Kaplan–Meier survival plot in BC patients. The database integrates gene expression and clinical data simultaneously. The two patient cohorts are compared by a Kaplan–Meier survival plot, and the hazard ratio with 95% confidence intervals and log rank p value are calculated [31]. GD3 synthase, GD2 synthase, and CASD1 expression are assessed in ER+/PR+ BC patients (upper) and ER-/PR-/Her2- BC patients (bottom). The black line represents the overall survival of patient with a low gene expression. The red line represents the overall survival of BC patients with high gene expression.