Table 6.
Reference | Cell Type | Title | Disease | Administration Procedure | Status |
---|---|---|---|---|---|
NCT01518842 Not applicable |
Bone marrow stem cells | Effect of Intravitreal Bone Marrow Stem Cells on Ischemic Retinopathy (RetinaCell) | Ischemic retinopathy, including diabetic retinopathy with severe loss of retinal capillaries | Intravitreal | Unknown |
NCT01736059 Phase I Study |
CD34+ autologous adult bone marrow stem cells intravitreal | Clinical Trial of Autologous Intravitreal Bone-marrow CD34+ Stem Cells for Retinopathy | Non-exudative age-related macular degeneration Diabetic retinopathy Retina vein occlusion Retinitis pigmentosa hereditary macular degeneration |
Intravitreal | Enrolling by invitation |
NCT03981549 Phase I/II Study |
CD34+ autologous bone marrow stem cells versus sham therapy |
Treatment of Central Retinal Vein Occlusion Using Stem Cells Study (TRUST) | Central retinal vein occlusion | Intravitreal | Recruiting |
NCT03403699 Not applicable |
Combination of CD34+CD45+ cells derived from human inducible pluripotent stem cells (iPSCs) with iPSCs derived from the mesoderm: vascular wall-derived progenitor cells or endothelial colony forming cells (ECFCs) subset (SSEA5-KNA+) | Human iPSC for Repair of Vasodegenerative Vessels in Diabetic Retinopathy | Diabetes complications Diabetic retinopathy |
Others: to test if the hiPSC-derived-mesoderm subset (SSEA5-KNA+) can revascularize vasodegenerative capillaries and if their reparative action can be enhanced by coinjection of CD34+CD45+ cells intravitreally. | Recruiting |
NCT03264976 Not applicable |
None | Role of the Serum Exosomal miRNA in Diabetic Retinopathy (DR) | Diabetic retinopathy | Validation of a diagnostic test based on exosomal miRNAs in serum samples that will be sequenced | Not yet recruiting |